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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b6a5c46981c5061b22495511ba9dd65cf2d34a1e10f5c400146afeae4817ac8' 
  AND token = 'j6eiV9vIevqAv1RR+sSJ0WJiSFeH0iIQWZxPKzS9PFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}