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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b72820d6b9e80d4c59e7ddca7401547856d3e862d2edbbf5009d464d75dacf8' 
  AND token = 'ewcecRb7PyPVdM6Aw6rDOHhMEE7v5BqDu0wQA1diE3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}