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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4f8ed41993983211ef049551522453dc29eb924ceac04fad6579ea7171ed86f' 
  AND token = '4GVC/a4cXC9JJLLketCYYTvpC/2Vk2eRhzHjxRE4yqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}