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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a66fd056820f4edc01fc6fb0f9d7d795d29759629f22be312146c85db0759c9' 
  AND token = 'N/InKfOwc/72xpx49/6AFKNi4Yd6BOOA1gyT/QvL65E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}