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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e156e7b0fd33f784ff9bd5a02578891eae70b4b0025c7fe49233fe649fb615c4' 
  AND token = 'wWL7renh4fE+Q8kd/asfz7HmvgaNUqfcnOMrm4hDT6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}