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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51349dc52bc605e3124680b536687f914d8b7a717975211dd4ea4e7161b75a37' 
  AND token = 'uFtCZdjcOP8n/0eUN5ur3aD3EL3Dx3JV+oLW869X1Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}