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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '385c674395884521911e29f552652b1c06dd292113ee1a5ecd60c2ad9f890004' 
  AND token = 'JG8jVEfA5sBMVq9qUBdCnTJ4a8x5/WSEVKk/ATWLKsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}