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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '073159a41d8f0b887870d2f2b32c83cd8b9a20b7117182591678a37f4d17b174' 
  AND token = 'O+LkyU7FKsgOeaFpVu0mYy52twi8pJ6AzgzdKDm0GcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}