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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '528882a545cea9e94ba3d9619976abac011800b6fa6ebeaa72c82871e5874322' 
  AND token = '4yneTB66FZ/GFRbYRK2g9u1vCG//1lN5OD/inH2+a8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}