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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a612691ae62e91e654507f3687c67d61bdfa55b0a052e82699ff03c31b4715c' 
  AND token = '1rjhsoAPhLszl2GnxcLjiIEQgFYkEsuoceJCIh+lZlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}