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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b75f2e3e43db1ee1f1e4aec098f7113d8237885495cf18dda05fe45e31cefd9' 
  AND token = 'EGJmdQEtoOBTz7YfeNnvLCqZ2SjL7mspbpFyykf2QAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}