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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '266e8378c5a33b637908f542ebf49d4360fc78035202a8f076ff0d9738baf5ba' 
  AND token = 'K05krz3aU1gxXt8xb31SpEe4PwpTYkM02mCdFIOvQIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}