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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '663bb443dffacd21e81b7671d387e3c12f4e62e3e52c1e998a04865fcff0d514' 
  AND token = 'XJd5nV1NBJ3LXji2YnyDkGYuhiC4bjHC9+w6jn1Nn1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}