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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4b1a66db480923528d7029784c3d4760d3c0f29eedfdd0c1fd581afdbf6f828' 
  AND token = 'wmb9Z4zYeuFKchwcRbqIIC76dZ82ZHCKHcWiyESZ3fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}