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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f57c6331090e45d413292db11c0e94c147c47dfd09980b60a33ef31f0230b6fd' 
  AND token = 'aneQvOM49MIgG9VXB4JM6xem3Xkh8b67EkqN7sv0B7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}