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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf0c5effb29876dda735f9f3b64c054841163f3fd8ce1a6be4e2e1f8a8e7c544' 
  AND token = '4W+M3rG2Y8mSTk6q4C0W94OUV+g08LuF9lfK6Gy3sgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}