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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '438aae74b43cf1726b6dfb1f6d8c18ee3b222ee7dac3205e5e3cd1db67628b66' 
  AND token = '6fSKHWlPP86KZWxszoxuK/BGis/QOJGGuYdtqB3e6Mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}