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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da461e3a870e6ce555a5f25915f2a9e10018c9bace9bd5cc32c43efc0746ee72' 
  AND token = 'g0yTGy146sueEsMgswVzDo8Mw0t+1IdksHdnyQJ2SKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}