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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216e4c6cef3583661cc2d69a5d4935e5a7faa26d524c72c954ab70d4cdcdc933' 
  AND token = 'oRp00/RZZTIkYIpn7FJ9PL4JfStc+1wVb4e25NvcTnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}