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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f074808386e4e74830f57e681a50390b7df87f498cd7d83979f7b84626f6568' 
  AND token = 'lKxJ7ht5l3HjqaBnOk4r022SBxlXuFU5iJeBJ8vElZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}