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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '477ef4323c72a9ad3052a2fbc8e9b39d1a389dbee9a6b81a0736ab2e513c1608' 
  AND token = 'nxPlSPgmuHuUAsytGwGkV2LEz4AA5e3RLyr6IbBYo/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}