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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fd61205c1299926205da554b59230922cb1750770379e42208c7b09cb726465' 
  AND token = '2/d5iKNRZmzHv+qMrWrB2RK8I6kj8s+icesnsZiFV2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}