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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cc59e7226caa91926af7dc7660431fe48d498dcf156f8709f4eb4f4436ea943' 
  AND token = 'PLOOsDonoooJFZw79vVQ26vOn60ZWg58ZnzZEzZ0SLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}