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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58fe2d13d7d451b38c628ff6879edd88662e82cf0a0df6b53bc6a918c7aeb3ff' 
  AND token = 'I0RFfEc+sDPVFwWM/s0d4WfYUNw2wjz4TwOBQtKnxzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}