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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae5e8d5a6fc1f7679c889149506951b048a1c1265c8c92f71c7663f548bf9f2c' 
  AND token = 'My+PWko2QJkOlC2erF9x95+IOiEpeM8K5wl0qaEAXuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}