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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4641098b562c679e469336b4b24a7c7200937f344092a1ae3f06980ab9df6c2' 
  AND token = 'EyX3ytjixhPjEnrka9SabHgRQHQFABwqXEO2SsOFlp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}