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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '537be43ae70d4c62fa551a3203515e70c9114a7101de625f212ffc2ef408d5de' 
  AND token = '9nAUs9Rlk2pQeHUXUbKtvmm/B6dLoSb+HgH2NXain8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}