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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35e780d81149ee2060f84073ebd5b2b1f7034b1643a9f6e451b4dd7ee82604d1' 
  AND token = 'amIXcqxgNE3Sg4c16Csj8Nklt3aVzrz+lpH0H6QkQHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}