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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '086c09f053320aa79782e8b20c12e92c1a52a06445ff071046bca19d615a5bfc' 
  AND token = 'IPe7Rf6uHpMzKzSEmJMX2KAzfb7qZpu0KOlM4mG4igA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}