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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9899f0e62de9fef75354055b9275bbe780e7486bce8bc920d04273262e219ec2' 
  AND token = 'lQjsdzci+YCav/n/Lcqu+zph+pJijAc1oaR6MIsA3FM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}