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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306b074e388d5d39b548317e38e3eca9b96ab03feaecd4b832edb52f8facbbc4' 
  AND token = 'zOJGpgWnAfwF0e/xbRQf/8AlUHcg2o0rc2WS6XOVnKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}