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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91d5e76399800855e1046b6050d6c9f24a60f955af640e798e29d40295e37be1' 
  AND token = 'd4SsfjY3vg0PY5OgcYKdEc4gXxF4pRpMaJ0gAu7vHJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}