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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f80803790cd85ec4d530a112331b01f478c8fea59d854a87a5be01143d841c' 
  AND token = 'q0IAmLRpBhIe8RBwGdNfVwphmjTjYnSowui36IbY9ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}