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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f03f5c25516a61ee35c993d06d8f294e5ba0c93e300cb88f5f17e5c6c6ca283' 
  AND token = '9AS7CdMpO8yumhgik+aR+CTiThQfnrzbN0gkjM/UDUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}