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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a901bb18b20da6a3f56de8d3fe8e83f7c52be6cab13f03050870007cdc02ddb1' 
  AND token = 'vMe5TiXFb4Bnr3yWOC+YU6qTDK3LmEiS5bI70Yq656I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}