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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4957432a6a6269da4d5bba568a60cfd3f7a19e4aca714f4a83a9e878b6da50' 
  AND token = 'au7/FwSX8e6TpCv7FLQQc4f3BKHY8qUZcXuovV1/rPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}