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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f21a316353ef1c2dbb8ec27435216a8f7d8642a6a70eedfc8ad1397109556af9' 
  AND token = 'RdMhn8Db04bGtxVue4QEg+Nt0e8jQZYaU6ZZGLowc0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}