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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c15d0bd661c8510fa294111165cccf344c094c03a5c8d27c1a679e2789cdae0' 
  AND token = 'EZf1U1fFGBoJtnIZ/qYNMKa8V1nySfIamdq9UBkueKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}