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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77c0fdfc1459b006ca6f706c8eda84505a99777bcd2af26d3412a6f265cd4b04' 
  AND token = 'k1gY2vMBDQ6R3Sod8EnacCB3nojmhytuFMpgEdkyeAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}