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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dec0d2ed25690fe167ac24f19613732bb1d49c38baca1685bb970de6614e5137' 
  AND token = '5shiPbdCP2xL33GDpwi9/XM61YAAQrndiRPSUeTE+do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}