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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9e99baa8b8a1dcdbb61414073182b9ca1e64542d75801ee866720d451b8d618' 
  AND token = '5CO4TwSUmAe/rzA9MN4zH8S2OWXoxDyRO91HQwi41aY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}