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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '667f8a3e542cfa79f1fe25327c7db9ae751346f14ba9ca0a303ae9173f7868db' 
  AND token = 'Tx+WYUxGrsgk0pmqoEZ3fOpWOrhmBTPeEKtALKRZOC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}