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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df7046309080215e7d2699164716260c2aa407cd373cbd0480418116b26e79f' 
  AND token = 'V1O/wdnax8IZ2u5PkvVWwUOHjS/VEphvu7TrtYmyCyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}