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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '784ef1fa9f0fa7724910d84350c41ee51b2c4e1e512f7ce368a665a054a95066' 
  AND token = 'dyeMCvr+XXHZCaqGSPLOp0JC91G/u7eLP7OOBPy3PZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}