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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae0a503456371e390c75aa7c45113f30da8e7e4750c41daa6e49a197e2112d06' 
  AND token = 'aKzU3Cx7dmH8QhxLKOQX+qPKxwhCtFqrntJ/NJ1B/hE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}