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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39a40502cefd110bbb2c0d16bf2ac7dbec9ea44f94a18c5f59e86c4acda6c898' 
  AND token = 'QzgDuQNGCwDUY6qq6m867wcFvG039+0Tm8OUCBPX30U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}