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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fd8a4080b21d6824cef3c4f29d1b44e632f073ba43b90ed14cf55ec3ad97c77' 
  AND token = 'Mxw74J+OtGf0xmyeNPt7l8RQ4VpYz9zGc26LbaoBvKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}