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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8652caa46daadb492127e60f478398473ca0fca995f9f67c00de5d5ce757e3e' 
  AND token = '4R1w2SX2OUVwFF9Tnj/eqSlvW/SSYQE7IPO7k2NruSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}