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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4a0d92a1573d76ad90373209bcd75774749820d80b71e72af79ee3c357f5053' 
  AND token = 'U05jXNsDJAqnpq3i16X4gF3BVcQGYD4VxF+BxQnfdo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}