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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10ad2b87c23626b5eadb8f93d3198e5525c58c2d92f266119c523061c51d28f' 
  AND token = 'oCgmL4fEyndy96gADC6bEszrw/XWXH4/QGh5+gF6PuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}